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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
RPS6KA5
All Species:
5.76
Human Site:
T27
Identified Species:
8.44
UniProt:
O75582
Number Species:
15
Phosphosite Substitution
Charge Score:
0.07
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O75582
NP_004746.2
802
89865
T27
D
G
G
E
Q
L
L
T
V
K
H
E
L
R
T
Chimpanzee
Pan troglodytes
XP_001140389
894
100719
V119
A
E
D
L
I
I
R
V
K
E
L
Y
T
F
C
Rhesus Macaque
Macaca mulatta
XP_001088246
1054
117436
T285
D
G
E
E
Q
L
L
T
V
K
H
E
L
R
T
Dog
Lupus familis
XP_547953
806
90703
E34
Y
S
E
G
E
V
Q
E
N
S
H
W
A
L
V
Cat
Felis silvestris
Mouse
Mus musculus
Q9Z2B9
773
85721
V30
G
H
E
E
K
V
S
V
E
N
F
A
L
L
K
Rat
Rattus norvegicus
Q63531
735
82865
L41
P
S
K
D
E
G
I
L
K
E
I
S
I
T
H
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506738
716
80894
S27
N
E
V
T
F
N
F
S
L
P
S
T
I
E
D
Chicken
Gallus gallus
Q5F3L1
789
89022
I36
G
H
A
E
K
V
G
I
E
N
F
E
L
L
K
Frog
Xenopus laevis
P10665
733
82620
V41
T
S
K
D
E
V
V
V
K
E
F
P
I
T
H
Zebra Danio
Brachydanio rerio
Q6PFQ0
740
83378
P32
G
H
Q
I
M
D
E
P
M
E
E
E
S
Y
T
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9V3I5
1207
137026
S210
A
A
A
A
S
K
A
S
S
S
T
T
P
S
Y
Honey Bee
Apis mellifera
XP_395099
910
102507
V37
T
I
V
E
E
P
I
V
I
E
E
R
N
Y
G
Nematode Worm
Caenorhab. elegans
Q18846
772
87050
L33
G
A
Y
G
K
V
F
L
V
R
K
V
G
G
K
Sea Urchin
Strong. purpuratus
XP_786494
918
102561
G30
V
F
L
V
R
K
V
G
N
H
N
Q
G
K
L
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q39030
471
53019
Baker's Yeast
Sacchar. cerevisiae
P18961
677
76646
G12
R
I
S
K
F
K
L
G
R
S
K
E
D
D
G
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
88.1
75
93.1
N.A.
62.8
41
N.A.
82.1
89.4
40
40.5
N.A.
28.5
45.7
46.8
53.3
Protein Similarity:
100
88.5
75.1
95.1
N.A.
76.6
57.9
N.A.
86.1
94.6
57.4
57.3
N.A.
40
62.3
63
66.2
P-Site Identity:
100
0
93.3
6.6
N.A.
13.3
0
N.A.
0
20
0
13.3
N.A.
0
6.6
6.6
0
P-Site Similarity:
100
13.3
93.3
20
N.A.
26.6
33.3
N.A.
26.6
33.3
40
26.6
N.A.
6.6
33.3
26.6
33.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
21.2
21.5
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
35
38.5
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
0
13.3
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
0
20
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
13
13
13
7
0
0
7
0
0
0
0
7
7
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
7
% C
% Asp:
13
0
7
13
0
7
0
0
0
0
0
0
7
7
7
% D
% Glu:
0
13
19
32
25
0
7
7
13
32
13
32
0
7
0
% E
% Phe:
0
7
0
0
13
0
13
0
0
0
19
0
0
7
0
% F
% Gly:
25
13
7
13
0
7
7
13
0
0
0
0
13
7
13
% G
% His:
0
19
0
0
0
0
0
0
0
7
19
0
0
0
13
% H
% Ile:
0
13
0
7
7
7
13
7
7
0
7
0
19
0
0
% I
% Lys:
0
0
13
7
19
19
0
0
19
13
13
0
0
7
19
% K
% Leu:
0
0
7
7
0
13
19
13
7
0
7
0
25
19
7
% L
% Met:
0
0
0
0
7
0
0
0
7
0
0
0
0
0
0
% M
% Asn:
7
0
0
0
0
7
0
0
13
13
7
0
7
0
0
% N
% Pro:
7
0
0
0
0
7
0
7
0
7
0
7
7
0
0
% P
% Gln:
0
0
7
0
13
0
7
0
0
0
0
7
0
0
0
% Q
% Arg:
7
0
0
0
7
0
7
0
7
7
0
7
0
13
0
% R
% Ser:
0
19
7
0
7
0
7
13
7
19
7
7
7
7
0
% S
% Thr:
13
0
0
7
0
0
0
13
0
0
7
13
7
13
19
% T
% Val:
7
0
13
7
0
32
13
25
19
0
0
7
0
0
7
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
7
0
0
0
% W
% Tyr:
7
0
7
0
0
0
0
0
0
0
0
7
0
13
7
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _